Original ArticleOpen Access

High Fluoride Intake and Low Calcium Alongwith Genetic Predisposition May Lead to Bone Weakness and Deformation

ยทยท
DOI: 10.23958/ijirms/vol04-i04/626ยท Pages: 296 to 298ยท Vol. 4, No. 04, (2019)ยท Published: April 28, 2019
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Abstract

Fluoride affects bone strength, by replacing hydroxyl ions in bone crystals to form fluoroapatite, and increasing both the osteoblast and osteoclast activity. Daily intake of naturally fluoridated water, is inevitable in many areas and countries throughout the world, it remains a major health issue as it has been suggested that fluorides may paradoxically aggravate osteoporosis and increase osteoporotic fractures and several epidemiological studies have been published showing that there is an increased rate of bone fractures i.e mostly hip fractures in older people in living in fluoridated areas. This study was carried out to ascertain the fact that high fluoride intake and low calcium may have on bone deformities in patients.

Author details
Mahendra Kumar Verma
Department of Paramedical Technology, NIMS University, Jaipur, Rajasthan
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Ravinder Pal Singh
College of Pharmacy, NIMS University, Jaipur, Rajasthan
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Manoj G Tyagi
Department of Paramedical Technology, NIMS University, Jaipur, Rajasthan
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