Abstract
In Cyprus: Among women aged 15-45 years of age - cervical cancer is the 3rd most common female cancer and is also the 3rd leading cause of female cancer deaths. The most commonly identified and well-known causative factor is HPV virus. Our case refers to a 32-year-old woman that had consecutive normal pap smear cytology results, for 11 years. At her last visit, a cervical sample was taken for HPV identification (a pilot program). The results revealed an infection with high-risk HPV strains. During the colposcopy that followed, HSIL was diagnosed and a loop excision was crucial to treat the precancerous lesion. This case highlights the primary causative factor of cervical cancer and underscores the importance of HPV DNA testing in the early identification of premalignant lesions.